Blepharochalasis Syndrome – Causes, Symptoms, Treatments & More


Nowadays, there are several people who are facing an eyelid issue, and in medical term, it is known as blepharochalasis syndrome. Yes, this is the eyelid issue that most of the people are facing today. Do you have this eyelid issue and want to know all about this issue?

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Well, I think it is very difficult to identify that you have blepharochalasis syndrome and also it is not so easy to get the best solution for this eyelid disorder. But, through some sources, I have collected some information related to this eyelid issue and the treatment procedure as well. So, do not panic, just go through this blog and know everything about blepharochalasis syndrome. But, first of all, let us know the meaning of blepharochalasis.

What Is The Meaning Of Blepharochalasis?


Blepharochalasis syndrome was firstly described by G.J. Beer in a textbook of 1817 and alter it was named by Emst Fuchsin the year 1896. This is an eyelid condition which consists of chronic skin changes and episodic inflammation. This eyelid issue is actually bilateral and it tends to manifest in the upper eyelids. However, sometimes this has been also seen that it is affecting the lower eyelids as well.

Blepharochalasis syndrome generally takes place in the people who are around 11 years old. Also, this eyelid conditions takes place in similar frequency in males as well as females. But, as per the survey, it has concluded that blepharochalasis syndrome occurs more in females than in males.

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Blepharochalasis is not a common disease that affects your upper eyelids. At first, during this eyelid issue, the upper eyelids become inflamed and then they swell up for several days at a time.

The distinctive feature of this disorder compared to other disorders that show the same symptoms is the frequent nature of it. Their disorders used to come and go in an irregular fashion. However, at the same time, it goes on the repeated episodes take their toll and then it gives rise to the serious other symptoms of the eyelids.

What Causes Blepharochalasis Syndrome

The actual blepharochalasis causes is still unknown. However, there are some factors that may lead to the development of blepharochalasis and they are as follows:

  • Vertebral Abnormalities
  • Renal Agencies
  • Congenital Heart Disease

Apart from these, there are some other factors as well that cause blepharochalasis syndrome. They are as follows:

How Can Blepharochalasis Syndrome Be Diagnosed?

blepharochalasis syndrome diagnosis

Well, do you know that there are several ways with the help of which one can easily diagnose? Yes, during this eyelid problem, a patient will have attacks of painless eyelid swelling. Some may notice stressful events preceding attacks of edema or even allergy. Some other may notice factors like fever, bee sting, crying, physical activity and more. Some ways with the help of Blepharochalasis can be diagnosed are as follows:

Physical Examination

Blepharochalasis is a kind of clinical diagnosis. If there are some characteristics that show eyelid erythema, edema and even conjunctival injections. Some other physical exams that may diagnose Blepharochalasis are:

  • Severe eyelid skin thinning
  • Subcutaneous telangectasia
  • Lacrimal gland prolapse
  • Entropion and ectropion
  • “Cigarette paper” or finely wrinkled skin
  • Proptosis
  • Orbital fat prolapsed
  • Lax eyelid skin which may obstruct vision
  • Pseudoepicanthal fold with atrophy of the nasal fat pad
  • Pigmentary skin changes
  • Levator dehiscence ptosis

Differential Diagnosis

Blepharochalasis syndrome can be easily mistaken for dermatochalasis. One of the great features of Blepharochalasis includes cigarette paper skin, episodic edema and subcutaneous telangiecta­sia. All these are absent in dermatochalasis. But, do you know what is the definition of dermatochalasis? Well, if you don’t know then look below:

Dermatochalasis is a just a medical issue which is defined as an excess of skin in the lower or upper eyelid. This is also known as “baggy eyes”. This eyelid issue may be congenital or acquired condition. This issue is generally treated with blepharoplasty surgery.

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Symptoms of Blepharochalasis Syndrome

It has been found that there are two basic stages involved in the development of Blepharochalasis. They are as follows:

  • Stage 1: The first stage involves the thinning out of the eyelids. It is repeatedly stretched by the swellings. This stage is generally called the ‘quiescent’ or ‘dormant’ stage by ophthalmologists.
  • Stage2: In the second stage, sometimes called the active stage. This does not involve the pain fortunately but merely it caused recurring swollen eyelids.

Apart from these two stages, there are some other complications that may take place at the starting stage of Blepharochalasis. They are as follows:

Ectropion: This eyelid takes place when the lower eyelid sags outwards and downward. This may even cause the development of corneal abrasion or corneal ulcers.

Entropion: This eyelid takes place when the blepharochalasis lower eyelid turns inwards and upward in the ways that the eyelashes touch the eye surface.

Blepharochalasis Syndrome Treatment

There are several Blepharochalasis treatment available that can be taken into consideration when you wish to get rid of Blepharochalasis syndrome.

Medical Therapy

There is not an established treatment available for Blepharochalasis. However, topical or systemic steroids, anti-inflammatory and antihistamines agents have not been yet shown to play an important role in the overall disease course.

Some experimental treatments have been reported that oral doxycycline has cured two patient’s eyelid edema and prevent attacks which is one of the causes of Blepharochalasis. Oral doxycycline is a known inhibitor of matrix metalloproteinases. The patients were treated with a dose of 50 mg po bid in the starting stage and then later they started treated with 25 mg po qod.

Apart from this, the oral sustained release acetazolamide at a dose of 250 mg po qd which is then reduced to periorbital edema and eyelid discomfort in a patient who refused eyelid surgery and failed treatment with oral corticosteroids.

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Surgery To Treat Blepharochalasis

Some surgical treatments are established to correct the complications of Blepharochalasis. Most common surgery is the Ptosis and the eyelid skin laxity. One should delay surgical correction until late in the disease course when attacks have become infrequent. Disease quiescence is generally recommended for six to twelve months prior to surgery.

People with Blepharochalasis issue can be corrected with levator aponeurosis dehiscence repair, eyelid tightening, fat grafting and canthal tendon reattachment.

The treatment procedures also involve these below treatments to get rid of Blepharochalasis:

  • Replacing atrophied tissue with fat grafts
  • Blepharoplasty procedure involves removal of atrophied internal tissue and excess skin
  • Operation on the canthus, the point at which the eyelids meet
  • Introducing a tuck as in plastic surgery


Blepharochalasis is an eyelid condition that takes place due to several causes, symptoms and more. However, you can also treat Blepharochalasis syndrome issue with the help of some effective treatments surgery and more.

You can try different surgeries as well to get rid of Blepharochalasis syndrome. They are very effective to cure this eyelid issue. Also, there are some medical therapies that can be treated to cure Blepharochalasis syndrome. You can also try them and notice that your Blepharochalasis issue has been cured. I hope this blog will be very effective for you to know everything about Blepharochalasis syndrome and its treatment as well.


Blepharochalasis Syndrome – Causes, Symptoms, Treatments & More
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Blepharochalasis Syndrome – Causes, Symptoms, Treatments & More
If you have Blepharochalasis syndrome then you should definitely know everything about this syndrome. All these treatments can really cure your bnlepharochalasis issue.
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